ABSTRACT
Objective To research the combined prognostic utility of NT-proBNP and hs-CTNI in NSTE-ACS risk stratification and early intervention therapy .Methods A total of 245 NSTE-ACS patients were divided to 4 groups(Aa ,Ab ,Ba ,Bb groups) ac-cording to immediate admission NT-proBNP and hs-CTNI .Patients were accepted percutaneous coronary intervention (PCI) ,coro-nary artery bypass grafting and conservative treatment were taken 6 months follow-up .Results The heart failure incidence of Aa group was significantly higher than Ba group(P0 .05) .In 6 months follow-up ,5 patients died and 10 patients accepted revascularization again because of severe angina and AMI .Conclusion In NSTE-ACS patient ,NT-proBNP and hs-CTNI elevation was closely related with severe coronary lesions and worse prediction ,which could undergo early in-tervention therapy .
ABSTRACT
Objective To assess the value of MR susceptibility weighted imaging(SWI) in the diagnosis of cerebral developmental venous anomaly(DVA). Methods Twenty-four patients with DVA were examined with 3.0T MR scanner, the sequences included spin echo T_1 WI, the turbo spin echo T_2 WI and SWI. The MR imaging features of DVA on SWI and conventional MR imaging were compared. Results Of the 24 cases with DVA, the lesions located in the white matter of frontal lobe(11 lesions), white mater of pa-rietal lobes (6 lesions), temporal lobes (2 lesions) and cerebellar hemispheres (5 lesions) respectively. Only 11 lesions were detected by pre-contrast MRI, which demonstrated as linear flow void in 4 cases and as radiated high signal intensity on T_2 WI in 7 cases. On contrast-enhanced MR imaging, all the lesions showed typical "caput medusae"-like enhancement. On SWI, all the lesions showed typical "caput medusae"-like low signal intensity. Conclusion SWI is sensitive to small venous anomaly and it can be a substitutive modality for contrast-enhanced MR imaging in the diagnosis and follow-up of DVA.
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Objective To study the appearance of MR diffusion weighted imaging in early stages of cartilage degeneration and to detect its values. Methods In 20 goat left knees, intra- articular injection of 5 units of papain was performed causing a loss of cartilage proteoglycan. Twenty right knees were used as control group. MR diffusion weighted imaging was performed at 24 hours after intra-articular injection of papain. ADC of each part of articular cartilage was measured and compared with each other. The proteoglycan content was measured biochemically and histochemicaUy. Routine MRI and DWI were performed in 100 patients with osteoarthritis and 20 healthy people. The ADC of each interested part of articular cartilage was measured and compared with each other. Results In experimental control group, the ADCav of articular cartilage was (14.2±2.3)×10-4 mm2/s. In early stages of cartilage degeneration group, the ADCav of articular cartilage was (17.5±4.2) × 10-4 mm2/s. The ADCav of the control group was lower than that of the early stages of cartilage degeneration group (t = 2.709 ; P = 0.016) . The proteloglyean content of articular cartilage was 4.22×10<'6> μg/kg in control group, and 0.82×10<'6>μg/kg in experimental group at 24 hours after injection of papain. The difference between control group and experimental group was significant (t = 2.705, P = 0.018). In healthy people, the ADCav of articular cartilage was (7.6±2. 2) × 10-4 mm2/s. In osteoarthritis group, the ADCav of articular cartilage was (10.3±4. 2) × 10-4 mm2/s. The ADCav in the healthy group was significantly lower than that in the osteoarthritis group (t = 2.609, P = 0.014). Conclusion DWI is an useful method in detecting early stages of cartilage degeneration which can not be showed on routine sequences.